What happens during sleep?

Autism Science Foundation Weekly Science Report

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22:08

Host Francesca Amiker sits down with directors Joe and Anthony Russo, producer Angela Russo-Otstot, stars Millie Bobby Brown and Chris Pratt, and more to uncover how family was the key to building the emotional core of The Electric State . From the Russos’ own experiences growing up in a large Italian family to the film’s central relationship between Michelle and her robot brother Kid Cosmo, family relationships both on and off of the set were the key to bringing The Electric State to life. Listen to more from Netflix Podcasts . State Secrets: Inside the Making of The Electric State is produced by Netflix and Treefort Media.…

рік тому 25:59

M4A•Головна епізоду

During sleep, your brain is still active. It is turning all those things you learned during the day into long term memories through connections between the thalamus, hippocampus and frontal cortex. What happens in Profound Autism? How does the brain work during sleep and how will this knowledge lead to better sleep in people? Are …

131 епізодів

#Science #Medicine #Autism Science Foundation #Social Sciences #Autism #Health and Well-Being #Mental Health #Autism Spectrum #Fitness

What happens during sleep?

Autism Science Foundation Weekly Science Report

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M4A•Головна епізоду

Continue reading "What happens during sleep?"

131 епізодів

#Science #Medicine #Autism Science Foundation #Social Sciences #Autism #Health and Well-Being #Mental Health #Autism Spectrum #Fitness

Wszystkie odcinki

1
Contextual Factors in Autism: What took us so long? 26:25

7 днів тому26:25

26:25

Contextual factors, or external factors, are environmental influences and can impact not just a diagnosis but the life course of a person with autism and their families. A recent commentary by autism researchers around the world highlights the importance of these factors and provides resources on how they can be collected in a rigorous, but accessible, way. Dr. Marsha Mailick, lead author of the commentary, discusses the definition of contextual factors, why they are important, and how they can influence development. Read the commentary – open access – here: https://onlinelibrary.wiley.com/doi/10.1002/aur.3312…

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Is folate an evidence-based treatment for autism? 19:00

25 днів тому19:00

19:00

Today’s #ASFpodcast explains the potential and the unknowns behind folate, known as leucovorin when prescribe, for treating autism. CBSNews reported on a “miraculous” study using leucovorin that will need further research before it lives up to the type. However, it is an example of how different biological markers may direct what treatments work best in what people, and possibly an example of precision medicine in ASD. Second, more of the mystery of the male/female diagnosis difference in ASD. How do genetics affect liability in males and females? It’s been well established females have more of a certain type of genetic variation, but females are less likely to be diagnosis. New results show that the liability for autism is the same in males and females (both are just as likely to receive a diagnosis based on their genetics), however these two sexes may have a different threshold for an autism diagnosis. Females may need more of these mutations to receive an autism diagnosis. Read more below: https://link.springer.com/article/10.1007/s00431-024-05762-6 https://pubmed.ncbi.nlm.nih.gov/27752075 https://pubmed.ncbi.nlm.nih.gov/39954678…

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An Explanation of Some of the Recent Scientific Research Announcements 18:14

6 weeks тому18:14

18:14

The past couple of weeks have been a flurry of decisions involving government funding for research and health and wellness services. It’s been difficult to understand their impact without understanding the process in which science is evaluated for funding and policies around support of universities where the research takes place. In this podcast, we will clarify what environmental factors are associated with autism (not vaccines), summarize how grants are reviewed and what effect stopping them will have, and explain new rules around how much money research institutions receive in order to support that research, those “indirect costs” and what cutting them will mean for Research Institutions. https://pubmed.ncbi.nlm.nih.gov/39891002 https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-068.html Click to access actinghhssecretarymemoaction2212025-1737591296147.pdf…

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How IQ impacts the “will do” of skills: adaptive behaviors 32:10

8 weeks тому32:10

32:10

On this week’s podcast, Dr. Elaine Clarke from @RutgersU discusses the role of adaptive behavior. This refers to the wide range of skills that a person with autism can exhibit. Can they hold a conversation? Dress themselves? Prepare a meal? These sets of skills are strongly influenced by cognitive ability. Dr. Clarke will talk about the link between cognitive ability and adaptive behaviors and while there may be differences in the abilities across the spectrum, it means clinicians and families need to aim for what works best for their individual child. Read more below: https://pubmed.ncbi.nlm.nih.gov/38317766 https://pubmed.ncbi.nlm.nih.gov/39679971 https://pubmed.ncbi.nlm.nih.gov/39056304…

1
Do Transcranial Magnetic Stimulation and Direct Current Stimulation help people with autism? The latest science here. 12:17

10 weeks тому12:17

12:17

Two therapies that are meant to alter brainwave activity, called Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation are receiving a lot of attention for potential efficacy in treating autism. They are non-invasive, which means treatment is provided on the scalp. While results vary, the overall evidence does not support these two interventions in helping to treat core autism features. However, as TMS is approved for depression and OCD, people should ask their doctors about these potential treatments if they suffer from these conditions. Learn more in the articles below: https://link.springer.com/article/10.1007/s00787-024-02635-z Click to access nihms-1934887.pdf https://academic.oup.com/cercor/article-abstract/34/13/8/7661139?redirectedFrom=fulltext&login=false…

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We missed one for the 2024 year end summary: Proof of the importance of genetic testing in autism 27:41

11 weeks тому27:41

27:41

It happens every year – this one belonged in the 2024 year end highlights but was published late in the year. Researchers at UCSD, UCLA and CHLA followed families with autism whose genetic test revealed a rare variant. Did it make a difference in care? Understanding? Referrals? If you are in need of a genetic test, here are some things to know: https://www.alliancegenda.org/genetic-testing Reference here: https://www.sciencedirect.com/science/article/pii/S1098360024002673…

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The 2024 Autism Science Year in Review 13:10

13 weeks тому13:10

13:10

New Technologies, New Data, New Solutions This year’s progress in autism research includes promising findings, clarifications, explanations, and the uncovering of new avenues of inquiry. The focus is now on personalized medicine: finding the right treatment for the right person at the right time through targeted interventions. Advances in technology and genetic testing are opening new avenues for therapeutics, rapid drug testing, and improved differentiation of subgroups of autism. 2024 Autism Science Review…

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Online autism assessments as a perk of the pandemic 17:52

14 weeks тому17:52

17:52

While it may not seem like it, the COVID-19 pandemic brought some advances in care and understanding for people on the spectrum. One example is the development and validity of remotely administered assessments that families can participate in from home rather than travel to a clinic. These tools were built out of necessity, and are evolving into a set of tools that can be used to build better outcome measures for clinical trials. This round focused on those with autism and a rare genetic variant or “neurogenetic syndromes” since these individuals have a known biological etiology of autism. However, they may be further improved to be utilized across the autism spectrum. https://pubmed.ncbi.nlm.nih.gov/39643599 https://pubmed.ncbi.nlm.nih.gov/39526825…

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An update on why there are fewer autistic females compared to males 17:46

15 weeks тому17:46

17:46

This week, special podcast correspondent #MiaKotikovski summarizes new research on the increasing prevalence of autism, with a focus on females. While the number of diagnosed females is increasing faster than the number for males, females assigned at birth still are less likely to receive a diagnosis than males. Additional evidence points to females having more genetic mutations and lower cognitive ability, so the questions remain: Are there females with autism who are just not getting diagnosed despite having all the autism features? Why not? Does autism in females “look” the same as autism in males? What sets them apart? These articles are all featured in the year-end highlight of research, so this is the time to get a deep explanation of the latest in sex differences in #autism. https://pubmed.ncbi.nlm.nih.gov/34563942 https://pubmed.ncbi.nlm.nih.gov/39334436 https://pubmed.ncbi.nlm.nih.gov/33966484…

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Synaptic Density and Autism, explained 12:58

17 weeks тому12:58

12:58

….or at a podcast with at least an attempt at an explanation of what synaptic density is and how it is affected in brains of people with autism. This week we review three convergent lines of evidence – whole brain, brain cell then genes within those brain cells – that show that the autistic brain has a decrease in cell-to-cell communication in multiple brain regions, leading to social communication impairments. https://www.science.org/doi/pdf/10.1126/science.adh2602?casa_token=bjtbuFi5U88AAAAA:_ffcE-pGCPxh4re24ix_xDgenAS1cAgDHLIMJJQCCG_1LvxaJKrGwEb9LFuMNsTYhvtGqRwro1A1Smc https://academic.oup.com/cercor/article-abstract/34/13/121/7661138?redirectedFrom=fulltext&login=false#no-access-message https://pubmed.ncbi.nlm.nih.gov/39367053…

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Health Concerns Across 3 Generations 24:18

19 weeks тому24:18

24:18

Are you the grandparent, cousin, aunt, uncle, sibling, or half-sibling of someone with autism and wondered “what is the likelihood of autism in families, and the likelihood of comorbid conditions if I have a family member with autism?” Researchers at the AJ Drexel Autism Research Institute and Aarhus University in Denmark collaborated to calculate probabilities … Continue reading "Health Concerns Across 3 Generations"…

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Stigma experienced around the world 16:44

20 weeks тому16:44

16:44

Despite many years fighting it, families with autism still experience societal stigma. The experiences depend on many factors, summarized in the October 21st podcast. This week, Mia Kotikovski explores cultural factors involved in stigma. As examples, she explores the literature from Asia, the Middle East and the United Kingdom, how they are different, and how … Continue reading "Stigma experienced around the world"…

1
The Importance of Model Systems 36:44

21 weeks тому36:44

36:44

Animal models of autism, including cell based models, have received criticism because autism is a uniquely human condition so there is no value in studying it in a model like a mouse or a cell. On the other hand, model systems have been used for decades to develop therapies for a myraid of other conditions … Continue reading "The Importance of Model Systems"…

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Where is autism stigma the worst in the world? 17:02

22 weeks тому17:02

17:02

This week, part 1 in cultural stigma around autism with Mia Kotikovski provides an overview of stigma, where it can come from across cultures and provides some examples of stigma in different countries. Different areas of the world are in different places in terms of their perceptions of autism, their needs for autism families, and … Continue reading "Where is autism stigma the worst in the world?"…

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Factors That Influence Heterogeity and How 34:00

23 weeks тому34:00