Кращі подкасти про Genotype (2024)

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Recap - SIS Genotyped Ram Task 18:23

11d ago18:23

18:23

We’re joined on this week’s episode of OviCast by Jaynell Anderson, Programme Manager with Sheep Ireland, to discuss the SIS Genotype ram task. With ram sales underway, Jaynell gives us a recap on what the requirements of the SIS ram task are for hill and lowland flocks and how to identify eligible SIS approved rams in sales catalogues and using th…

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cfDNA Fetal RBC Genotyping in Alloimmunized Pregnancies: July 2024 NEW DATA 23:19

15d ago23:19

23:19

In September 2022, a cell-free DNA assay using next-generation sequencing and quantitative counting tech for fetal antigen status determination became clinically available in the USA. This allowed maternal screening for fetal RBC genotypes for RH negative patients. This test was recognized by thre ACOG in March 2024 as one option to “triage” anti-D…

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The Return to LT-O-Whole Blood (LTOWB) for OB Transfusion 39:51

2d ago39:51

39:51

Prior to the 1970s, when component therapy became the preferred method of resuscitation, whole blood (WB) was the resuscitative medium of choice for hemorrhagic shock. In modern medicine, sometimes it turns out that the old way is better than the new…and using whole blood for transfusions is one example. Research is emerging that shows whole blood …

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2024 CDC MEC UPDATE! HOT OFF THE PRESS! 51:05

4d ago51:05

51:05

MEC CHANGES ARE HERE! During January 2022, the CDC held virtual scoping meetings that included 27 participants with expertise in contraception, adolescent health, and thrombosis, as well as representatives from partner organizations, to solicit their individual input on the scope for updating both the 2016 U.S. MEC. The 27 invited participants repr…

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Is autumn reseeding an option? 25:37

4d ago25:37

25:37

We’re joined on this week’s OviCast by Dr Philip Creighton to discuss autumn redesign. We start by discussing the impact of timing on reseeds. We discuss field prep, different reseeding methods and their suitability and fertiliser and lime applications. Philip also explains variety selection and the inclusion of clover, plus we discuss post-sowing …

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Just Jungle - Taking It Back EP 2 - G Skool 4:16

6d ago4:16

4:16

Buy : https://genotypejjungle.bandcamp.com/album/just-jungle-taking-it-back-ep-2-g-skoolTracks : 1. Bredrin From Space2. Riddem Emphasis3. Squat Rave4. Ear Sharp5. HumidSocial Links :Soundcloud : https://www.soundcloud.com/genotype-justjungle-1Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungleGenotype & Just J…

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New Non-Estrogen Medication for Hot Flashes? Veozah's Competitor 24:04

8d ago24:04

24:04

In May 2023, the FDA approved fezolinetant (Veozah), an oral medication that's the first neurokinin 3 (NK3) receptor antagonist to treat moderate to severe hot flashes caused by menopause. Now, a separate oral medication which blocks the NK 1 and 3 receptor iis on the scene. Although not yet FDA approved, the published phase 1, 2, and 3 data make t…

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Antepartum AI for Stillbirth Prevention 35:37

10d ago35:37

35:37

Artificial Intelligence (AI) has arrived. Machine Learningis a form of AI which is being investigated/used for improving maternal outcomes. The UK has already launched the TOMMY APP (through the RCOG) for use to reduce PTB and stillbirths in the UK. In this episode we will highlight a new systematic review which assessed Machine Learning’s ability …

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TWiEVO 104: Wooly mammoth prosciutto 1:17:37

11d ago1:17:37

1:17:37

Nels and Vincent discuss the genome sequence of an ancient wooly mammoth, which shows that the three-dimensional architecture of the DNA can persist after 50,000 years. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode Join the MicrobeTV Discord ser…

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Maternal Obesity and SUID: New Data 33:54

12d ago33:54

33:54

We all are aware that multiple adverse obstetrical outcomes have been linked to maternal obesity, such as stillbirth, preterm birth, NICUs admission, and congenital anomalies. But once delivery and hospital discharge occurs uneventfully, a new cohort study is raising the alarm for another possible adverse event up until the child’s first year of li…

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NEW Clinical Practice Update (Aug 2024) 16:56

13d ago16:56

16:56

Our immediate past episode summarized a validation study of cell-free DNA (cfDNA) isolated from maternal plasma for fetal RBC genotyping in alloimmunized patients. And now, in this episode, we will highlight a BRAND NEW ACOG Clinical Practice Update on this very subject! YEP... we now have new ACOG guidance regarding using maternal derived cfDNA fo…

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Skyrocketing Sex Strangulation Rates: The Alert 45:15

16d ago45:15

45:15

First off, let’s all agree that everyone has a different STYLE of sexual intimacy, and that’s OK. Yep, we all understand that there's always been a lot of sexual act “diversity” in the world… and throughout history. But there is a more recent trend that has increased in popularity, some surveys attribute it to its representation in pornography, tha…

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Candida as IAI & Perinatal Sepsis? YES. 38:50

18d ago38:50

38:50

Candida in women is being right? Afterall, vulvovaginal candidiasis during pregnancy is common. Candida species may be isolated from the vagina of 15 %-21% of nonpregnant women; this rate increases to 30% during pregnancy. While it is generally benign and isolated to the vagina clinically, some Candida species have the capacity to be troublemakers.…

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Grass update & management tips for the coming weeks 9:39

19d ago9:39

9:39

Catherine Egan, host of the Beef Edge podcast, joins us on this week’s OviCast as we catch up with Grass10 advisor, Niamh Doyle, to get an update on the current situation and discuss management tips in the coming weeks. Niamh first highlights the factors that have limited grass growth over the last number of months. She also comments on the long te…

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The New PreTRM Biomarker Test 41:05

20d ago41:05

41:05

Biomarker testing has arrived in Obstetrics. Of course, we have been using some biomarkers for years, like PAMG1 (Amnisure) and AFP+ILGFBP1 (ROM Plus) for ROM evaluation. In May 2023, the FDA cleared Thermo Fisher Scientific's maternal serum biomarker test for prediction of preeclampsia with severe features in hospitalized patients (and we have a p…

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Sequential CX Ripening: Which Should Be First? 45:52

21d ago45:52

45:52

Published studies, including 2 large network meta-analyses, support the safety and efficacy of misoprostol (PG E1) when used for cervical ripening and labor induction. Based on cumulative data, misoprostol administered vaginally at doses of 50 μg has the highest probability of achieving vaginal delivery within 24 hours. Prostaglandin E2 also has pr…

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Latent TB Treatment in OB 40:08

23d ago40:08

40:08

Tuberculosis (TB) was historically called "consumption" due to the dramatic weight loss and wasting away experienced by patients. The modern name "tuberculosis" was first published by J. L. Schönlein in 1832. Today, between 3% and 5% of the U.S. population are estimated to be living with latent TB infection. Contrast that with the worldwide statist…

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S.4 Ep.3 - Coach Masterclass: Greg Mikolap from ICON 49:40

25d ago49:40

49:40

Have a comment? I'd love to hear from you! S.4 Ep.3 - Coach Masterclass: Greg Mikolap from ICON This is the second of a series of interviews of local (to me) established coaches, PTs and gym owners. Todays guest is Greg Mikolop owner of ICON in Maidenhead, Berkshire. I've known him for several years, we worked together for a few years as freelance …

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Previable and Periviable PPROM (NEW SMFM CS #71) 51:46

26d ago51:46

51:46

Approximately 0.5% of all births occur before the 3rd trimester of pregnancy, and very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. Preterm prelabor rupture of membranes (PPROM) is a known risk factor for preterm birth and is responsible for 30–40% of preterm deliveries. While PROM occurs around 8% …

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Toxic Tampons?! 34:26

27d ago34:26

34:26

Researchers estimate that more than 100 million women in over 120 countries use tampons during their menstrual cycle. Tampons are generally considered safe and healthy menstrual products. However, a new study conducted by researchers at the UC Berkeley School of Public Health has identified the presence of 16 different heavy metals in tampons from …

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Monitoring parasite burden and interpreting the results 15:21

28d ago15:21

15:21

This week we talk to Dr Orla Keane about monitoring the parasite challenge in lambs. We discuss the challenge stomach worms poses from this point of the season onward with Orla talking about using faecal sampling to monitor worm burden, explaining the process, what’s being tested and what the results mean. Orla also discusses the thresholds for dos…

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Does Summer Heat Imprint Childhood Cancer In-Utero? 42:24

29d ago42:24

42:24

It's Summer…and its getting HOT in here! Although the effect of heatwaves in pregnancy has been studied various times, the data remains limited because these studies are observational, with very heterogenous populations, so its hard to prove causation between heat exposure and adverse outcomes. Nonetheless, these associations are indeed concerning.…

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New Fast Track Designation for ENDO DX tool 29:51

1M ago29:51

29:51

Up to 1 in 10 reproductive-aged women are impacted by endometriosis. Dysmenorrhea is the most common pelvic complaint of adolescents. While most cases of primary dysmenorrhea in adolescents will be primary dysmenorrhea, Endo remains a possibility especially after 2-3 years of progressive symptoms. Although the true prevalence of endometriosis in ad…

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Well, That's Interesting...Say Whaaaat? 23:28

1M ago23:28

23:28

Well, sometimes the "traditional", evidence-based recommendations don't have the desired result they are supposed to. When the "usual and standard" ways of doing things fail, its time for "shared-decision making"! In this episode, we will highlight, and give KUDDOS, to an OB care team who exampled thinking outside-the-box in order to care for an ac…

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New Data (July 8, 2024) for Maternal RSV Vaccine 39:23

1M ago39:23

39:23

RSV season is just around the corner (Fall and Winter months). Newborns are 16x more likely to be hospitalized with serious RSV lung infection than the flu. On August 21, 2023, the FDA approved the first RSV vaccine, Abrysvo, for use in pregnant individuals to protect newborns and infants against severe RSV disease in the first 6 months after birth…

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TWiEVO 103: Change the world by duplicating yourself 1:38:49

1M ago1:38:49

1:38:49

Nels and Vincent explore a direct experimental test of Ohno’s Hypothesis, which states that gene duplication can help genes tolerate new mutations and thus facilitates the evolution of new phenotypes. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episod…

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Is Risk-Reducing OS for Ov Ca Overrated? 47:21

1M ago47:21

47:21

A substantial collection of evidence indicates that the fallopian tube serves as the primary site of origin for a large portion of high-grade serous ovarian cancers. As a result, clinical practice guidelines (including from the ACOG) recommend salpingectomy for permanent contraception- when necessary- rather than simple tubal ligation. But an Augus…

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SAB: Which Genetic Test is Which, and When? 36:57

1M ago36:57

36:57

Approximately 20% to 25% of pregnancies end in miscarriage, and there are many medical reasons why it may occur. About half are caused by chromosome aneuploidy. However, less than 5% of women will experience a second first trimester loss, and less than 1% will experience three early losses. The incidence of early spontaneous pregnancy loss increase…

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Do Fireworks Harm a Pregnancy? 17:24

1M ago17:24

17:24

Happy Independence Day, America! We hope you are enjoying this wonderful, national holiday. Yep...Its a PARTY in the USA! In light of the festivities, here's a clinical question for us: Do fireworks affect the fetus? Even broader than that, do loud sounds in general affect the developing child? The answer is both YES and NO. Listen in to this short…

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Adolescents in the ED Need BC! 26:42

1M ago26:42

26:42

(Here’s a WONDERFUL QI Project for this New Residency Academic Year) With 70.8% of pregnancies among adolescents being unintended, there is a clear need for increased access to contraceptive services. Many adolescents use the emergency department (ED) as their primary healthcare source, highlighting the importance of providing comprehensive sexual …

1
Fear the 37.5-37.9 °C Temp with PROM? 36:21

1M ago36:21

36:21

PROM occurs in approximately 10% of pregnancies and leads to a risk of IAI in women that is 3 times higher than that in non-PROM women. The risk of early-onset sepsis of neonates born to mothers exposed to PROM is 20 times higher than in non-PROM mothers. An increasing time period with PROM increases the risk of infection for both mothers and newbo…

1
THANK YOU (for Daniel and Isaac) 5:33

1M ago5:33

5:33

Podcast Family, I hope this episode gives you pause and brightens your day 🌞. Just a quick work and acknowledgement to likley our YOUNGEST podcast family member and his mother, a Co-OBGYN preparing for oral Boards. 👏👏 Let this speak to you as the message spoke to me! (and introducing callmestevieray & Connor Price, whose words/song- “GRATEFUL”- al…

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Do OCPS Cause Hypothyroidism? 34:54

1M ago34:54

34:54

Oral Hormonal contraception gets the blame for a lot ofthings, including the development of hypothyroidism. Hypothyroidism is one of the most common endocrine disorders affecting 5 to 10 times more women thanmen, and its prevalence increases with age. This association of OCPs with hypothyroidism comes from a controversial article in BMJ published i…

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Grazing Focus: Grass supply, sward quality and fertiliser 16:32

1M ago16:32

16:32

On this week’s OviCast we’re taking a grazing focus and are joined by Philip Creighton. We discuss grass supply and sward quality and some of the factors that are influencing it at the moment. We move on to discuss management options for the coming weeks and finish up the episode discussing fertiliser applications. For more episodes from the OviCas…

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PROM: Pit or Cytotec? 23:32

2M ago23:32

23:32

Podcast Fam, on March 27, 2024 our episode was called "Balloon for PROM: Yea or Nay". Although mechanical cervical balloons for induction were the focus, we also discussed which medication is better (based on published data) for labor induction after PROM. Well, in this episode, we pick up from March with ANOTHER NEW STUDY released today (June 25, …

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Maternal Stress & The Fetal Brain 33:31

2M ago33:31

33:31

Anxiety disorders are the most common mental health issue in the United States, affecting nearly 1 in 5 adults, or 40 million people. Another 19 million adults – 8% of the population – has depression. Prenatal mood disturbances are known to affect the fetal brain, and endocrine system. Left amygdalar volumes were smaller in newborns whose mothers h…

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OB EPO Use & Blood Salvage at CS (IOCS) 41:26

2M ago41:26

41:26

Respect for patient autonomy is a fundamental part of the clinician-patient relationship and discussion of healthcare interventions. Some patients decline transfusion of blood products, either for religious or non-religious reasons, but most frequently as part of the Jehovah’s Witness faith. Acceptance of, and decision-making, surrounding blood pro…

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Time to wean? 33:17

2M ago33:17

33:17

Sheep Specialist, Michael Gottstein, joins us on this week’s OviCast to discuss weaning options on farms. We discuss the current situation on farms, challenges with grass quality and why weaning now is beneficial. Michael explains the weaning process with some useful tips and management of the ewes and lambs post-weaning. We finish up discussing so…

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Sildenafil Cream for Women? “New” Data (June 18, 2024) 43:42

2M ago43:42

43:42

"HSDD" as a diagnosis has been gone for some time. According to the ACOG, the DSM-V defines the combined entity of female sexual interest/arousal disorder as a complete lack of or a substantial decrease in at least three of the following symptoms for at least six months: interest in sexual activity and sexual or erotic thoughts or fantasies. This i…

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Just Jungle - G Skool 27 5:19

2M ago5:19

5:19

Just Jungle - G Skool 27Buy : https://genotypejjungle.bandcamp.com/album/just-jungle-g-skool-27Tracks :1. Crisis2. Lockheed3. Moray4. Goosebumps5. Early ReflectionSocial Links :Soundcloud : https://www.soundcloud.com/genotype-justjungle-1Bandcamphttp://genotypejjungle.bandcamp.com/Instagramhttp://Instagram.com/genotypejjungleGenotype & Just Jungle …

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More PP HTN NEWS (June 12, 2024 Data) 33:10

2M ago33:10

33:10

Hypertensive disorders of pregnancy (HDP), including chronic hypertension, gestational hypertension, and pre-eclampsia, are increasingly common in the United States, complicating close to 15% of births, and the incidence is continuing to rise! On this show we have addressed medical management of urgent hypertension in pregnancy and in the immediate…

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IOPP For Post CS Opioids “New Data” 28:42

2M ago28:42

28:42

At time of post cesarean discharge, most providers prescribe a fixed number of opioid tablets. However, past data has shown that most patients don't use all the opioids they are prescribed. This leads to an excess of opioids in the community, which can ultimately lead to misuse and diversion. In this episode, we will highlight a new publication fro…

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(You ASKED) TOLAC IOL or Expectant Care: PART 2! 24:17

2M ago24:17

24:17

Podcast Family, this episode has 2 parts: 1. First, a "non-medical" little life lesson that I heard recently which I will share with you...I hope it ENCOURAGES you, and 2. The MEDICAL part, which comes from Paul- one of our podcast family members. Paul had a GREAT question regarding the data covered in our immediate PAST episode on TOLAC....listen …

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Focus on wool quality and shearing 26:50

2M ago26:50

26:50

Jayne Harkness-Bones, Depot Manager with Ulster Wool, joins us for this week’s OviCast to discuss the factors that influence the quality of wool, the challenges in the marketplace in recent years and what happens to the wool from purchase until it reaches market. We talk about shearing, wool handling and storage, with Jayne highlighting some simple…

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TOLAC: IOL at 39 Wks or Wait? 25:59

2M ago25:59

25:59

After a primary CS, the decision to undergo trial of labor after cesarean (TOLAC) or schedule a repeat cesarean birth is one in which a patient’s values and preferences should be prioritized in a process of shared decision making. Some clinicians elect to utilize a TOLAC calculator as part of the shared decision-making process, while others use a m…

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IM Vit K Avoidance at Birth: Alternatives? 35:51

2M ago35:51

35:51

Hemorrhagic disease of the newborn (HDNB) was first identified over a century ago, and presents as unexpected bleeding, often with gastrointestinal hemorrhage, ecchymosis and, in many cases, intracranial hemorrhage. In newborns, HDNB is typically caused by vitamin K deficiency as neonates are innately deficient in vitamin K secondary to very little…

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🔥NEW PRACTICE UPDATE: Paternal & Fetal Genotyping (cfDNA) in Alloimmunized Pregnancy 24:20

2M ago24:20

24:20

Proving that our podcast tagline, “Medicine Moves Fast” is true… this episode highlights something that is, once again, 🔥🔥🔥 Off the Press! on June 4, 2024, the ACOG released a new Practice Update regarding the determination of paternal and fetal RBC genotyping in pregnancies affected by alloimmunization. This builds upon and updates PB #192 from 20…

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cCMV (Part 2): Prevention, and Care. 22:01

2M ago22:01

22:01

June is CMV awareness month. And that’s the keyword there… Awareness! The way we prevent CMV transmission is by awareness. It would be great to have a vaccine against this virus, but we just don’t…yet. Until a safe and effective CMV vaccine is clinically available, primary prevention of cCMV relies on patient education and hygiene measures. In this…

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