50. Pioneering Bioorthogonal Chemistry w/ Carolyn Bertozzi - Professor @ Stanford & 2022 Nobel Laureate

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Carolyn Bertozzi is the Anne T. and Robert M. Bass Professor of Chemistry and Professor of Chemical & Systems Biology (by courtesy) at Stanford University, the Baker Family Director at Sarafan ChEM-H, and an Investigator of the Howard Hughes Medical Institute. She completed her undergraduate degree in Chemistry from Harvard University in 1988 and her Ph.D. in Chemistry from UC Berkeley in 1993. After completing postdoctoral work at UCSF in the field of cellular immunology, she joined the UC Berkeley faculty in 1996. In June 2015, she joined the faculty at Stanford University as an Institute Scholar at Sarafan ChEM-H.

Bertozzi's research interests span the disciplines of chemistry and biology. She invented the concept of “bioorthogonal chemistry” and has widely applied such reactions to study biological processes and build new types of molecular therapeutics. As well, her lab studies the roles of cell surface glycosylation in human health and disease. Her lab focuses on profiling changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and exploiting this information for development of diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.

Bertozzi has been recognized with many honors and awards for both her research and teaching accomplishments. She is an elected member of the National Academy of Sciences, the National Academy of Medicine, and the German Academy of Sciences Leopoldina, and she is a Foriegn Fellow of the Royal Society, UK. Her efforts in undergraduate education have earned her the UC Berkeley Distinguished Teaching Award and the Donald Sterling Noyce Prize for Excellence in Undergraduate Teaching. Some awards of note include the Lemelson-MIT award for inventors, Ernst Schering Prize, MacArthur Foundation Fellowship, the ACS Award in Pure Chemistry, and just last week, the 2022 Nobel Prize in Chemistry.

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