Impact of AI in Rare Disease Trials with Scott Schliebner

BioTalk Unzipped

Impact of AI in Rare Disease Trials with Scott Schliebner

Summary

In this episode, the hosts welcome Scott Schliebner as their guest and kick off with a charitable act, donating to Rare Givers. They delve into the Epitomee weight loss capsule's potential impact, then shift to discussing the challenges of establishing a North American infrastructure for a MedTech CRO, navigating cross-cultural dynamics. Later, they investigate the transformative potential of AI and machine learning in clinical trials. Scott Schliebner weighs in on the intricacies of rare disease trials, emphasizing patient recruitment hurdles, interdisciplinary care, and stakeholder collaboration. The conversation also delves into AI's role in addressing these challenges, particularly in patient recruitment and data analysis.

#clinicaltrials #science #ai #raredisease #drugdevelopment
Takeaways

• Rare Givers (https://www.raregivers.global/) is a nonprofit organization that supports caregivers in the rare disease space.

• The Epitome weight loss capsule is an innovative medical device that tricks the body into feeling full, aiding in weight loss.

• Building a North American infrastructure for a MedTech CRO requires navigating cultural differences and finding key leaders who can adapt to a startup environment.

• AI and machine learning have the potential to transform clinical trials by improving drug discovery, analyzing large datasets, and enhancing patient retention.

Chapters

00:00 - Introduction and Charity Donation - Rare Givers

02:30 - Discussion on Rare Givers

04:08 - What inspired Scott to the Clinical space

06:12 - New News: Epitomee Weight Loss Capsule

11:25 - Epitomee target drug delivery application weight loss competition with Wegovy

14:05 - Building a North American infrastructure for EU-based MedTech focused CRO

16:35 - Cultural idiosyncrasies to be aware of doing business with different countries

23:53 - The Impact of AI and Machine Learning, and generative AI in Clinical Trials, drug development, FDA compliance, and quality control

30:13 - Understanding Rare Disease Trials, and overcoming challenges

33:12 - Is it a Zebra or a Horse?

DONATE to Rare Givers:

https://www.raregivers.global/

How to reach us:

Scott Schliebner

https://www.linkedin.com/in/scott-schliebner-1087789/

Dr. Chad Briscoe

https://www.linkedin.com/in/chadbriscoe/

Gregory Austin

https://www.linkedin.com/in/gregoryaustin1/

New News Link:

• Epitomee® announces the filing of a novel Weight Loss Capsule for FDA clearance

• https://www.prnewswire.com/news-releases/epitomee-announces-the-filing-of-a-novel-weight-loss-capsule-for-fda-clearance-302081225.html

• NIH Study publication: Safety, tolerability and efficacy of a novel self‐use biodegradable device for management of obesity

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700511/

Image Credits

Zebra - https://www.rarediseaseday.org/event/6th-annual-rare-disease-day-virtual-race/