Cardiovascular Physiology Categorisation Drills for the exam PART 1

Anaesthesia Coffee Break

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In this episode we cover categorisation of core cardiovascular topics
Here is a brief summary:

Hypotension

Preload
Rate
Rhythm
Contractility
Afterload

Or Shock
Hypovolaemia
Cardiogenic
Distributive
Obstructive

O2 supply demand
Supply
= o2 flux or delivery to heart
CBF x o2 content (Hb, sats, PO2)
CVR and CPP
CVResistance = metabolic, myogenic, neural, physical compression, viscosity, pathology
CPP = Cor Pressure – RAP or LVP.

O2 extraction.
High basal extraction of 55-65%
other tissues only 25%
so O2 demand is met by increasing CBF

Demand
Depends on Metabolic rate and myocardial work
Wall tension – PL and AL
Contractility
HR
Rhythms

Wall thickness
Basal rate
Type of work (pressure > volume work)
Electrical activation

When this is unbalanced = ischaemia

Determinants of coronary vasc resistance

Resistance = pressure difference / flow = corPP/ CBF

= 8nl/Pi R4. (n = eta)

Radius
Neural
Physical – compression, HR,
Pathology
Autoregulation
Metabolic
Myogenic
Viscosity

Coronary blood flow

= CPP/CVR

Neural
Physical
- Compression
HR
Viscosity
Autoreg
- Metabolic
- Myogenic: A myogenic response refers to the intrinsic tendency of vascular smooth muscle to contract in response to increased distending pressure and to relax in response to decreased distending pressure.

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