Кращі подкасти про Biotech Nation (2024)

1
70% of Breast Cancers and a Link to Prostate Cancer... Dr. Sean Bohen, President & CEO, Olema Oncology 23:02

16h ago23:02

23:02

This week on BioTech Nation, we explore new efforts in treating cancer with Dr. Sean Bohen, President and CEO of Olema Oncology. We discuss progress in treating breast cancer, particularly ER+/HER2- breast cancer, which accounts for 70% of diagnoses this year. They examine the biology behind these cancers and how Olema's lead compound, palbociclib,…

1
Tiny RNAs, Big Cures!!! Dr. Sanjay Shukla, President and CEO, ATyr (ah-tire) Pharma 19:54

8d ago19:54

19:54

This week - Dr. Sanjay Shukla, CEO of Atyr Pharma, discusses the revolutionary potential of mRNA technology in creating new medicines. They explore Atyr's pioneering approach to leveraging tRNA fragments for treating pulmonary sarcoidosis and other organ-specific conditions, aiming to improve patient outcomes while minimizing reliance on convention…

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How Can a Treatment Become a Vaccine??? Dr. Peter DeMuth, Chief Scientific Officer at Elicio Therapeutics 23:33

15d ago23:33

23:33

Dr. Peter DeMuth, Chief Scientific Officer of Elicio Therapeutics, discusses the revolutionary approach of detecting cancer at its earliest stages through circulating tumor DNA (ctDNA) tests. Highlighting their innovative treatment method, which aims to train the body's immune cells to recognize and destroy cancer cells, the episode explores the po…

1
Cancer Vaccines??? Dr. Chris Pirie, Co-Founder & COO of HDT Bio 17:08

22d ago17:08

17:08

In this week's episode, Dr. Moira Gunn interviews Dr. Chris Pirie from HDT Bio about their novel approach to cancer prevention through vaccines. They discuss leveraging mRNA technology to target specific tumor mutations and prime the immune system to recognize and eliminate cancer cells. Dr. Pirie highlights ongoing efforts to develop vaccines for …

1
Redefining Acute Myeloid Leukemia (AML) Treatment!!! Dr. Robert Ang, President & CEO of Vor Biopharma 15:20

29d ago15:20

15:20

This week I speak with Dr. Robert Ang from Vor Biopharma about their innovative approach to treating acute myeloid leukemia (AML). AML is a type of blood cancer that affects the bone marrow, leading to the overgrowth of cancerous cells. Dr. Ang explains that traditional treatments, such as chemotherapy and stem cell transplants, have limitations an…

1
Fighting Inflammation, and Alzheimer's??? Dr. David Bearss, President & CEO Halia Therapeutics 28:57

1M ago28:57

28:57

In this week's episode of BioTech Nation, Dr. David Bearss, President and CEO of Halia Therapeutics, discusses inflammation and its reduction over a lifetime and in response to various incidents. He unveils the inflammasome, a recently discovered protein complex critical in regulating inflammatory responses and its potential in treating chronic dis…

1
Food as Medicine, A Personalized Prescription... Dr. Daniel Kraft, Tech Nation Health Chief Correspondent 10:21

1M ago10:21

10:21

Tech Nation Health, Chief Correspondent Dr. Daniel Kraft discusses the concept of "food as medicine." Dr. Kraft emphasizes the evolving understanding of nutrition and its profound impact on health, advocating for a shift towards personalized nutrition using cutting-edge technologies. From continuous glucose monitors to AI-powered apps and sensor to…

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Repairing Minds, Naturally??? Mark Litton, President & CEO, Athira Pharma 22:38

2M ago22:38

22:38

Alzheimer’s, Parkinson’s dementia, and other neurodegenerative diseases continue to be challenging, but now new science has led to a better understanding of the natural repair mechanisms in the brain. This, in turn, has generated new options for innovative treatments, and one such approach has entered late-stage human clinical trials. Dr. Mark Litt…

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Combatting Blood Clots!!! Dr. Daniel Bloomfield, Chief Medical Officer, Anthos Therapeutics 14:31

2M ago14:31

14:31

This week, Dr. Daniel Bloomfield from Anthos Therapeutics discusses the prevalence and dangers of blood clots, particularly in patients with cancer. Dr. Bloomfield explains the difference between normal and abnormal blood clotting, the risks associated with blood clots in arteries and veins, and the challenges in balancing clot prevention with the …

1
Heartburn, GERD, Cancer??? Dr. Lishan Aklog, CEO of Lucid Diagnostics 22:59

2M ago22:59

22:59

Dr. Lishan Aklog from Lucid Diagnostics tells us about the path from GERD to, unfortunately, esophageal cancer, and about Lucid’s two-minute diagnostic test which can detect precancerous cells.Moira Gunn

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From Tummy Tucks to Drug Trials??? Dr. Eric Merle, Chief Business Innovation Officer, GenoSkin 14:23

2M ago14:23

14:23

Dr. Eric Merle from GenoSkin talks about how they are transforming drug discovery using discarded human skin from surgeries like tummy tucks, revolutionizing the process and accelerating drug development timelines.Moira Gunn

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One Drug, Many Diseases??? Dr. David Fajgenbaum, UPenn School of Medicine Professor and President of Every Cure 27:56

3M ago27:56

27:56

Not just seeking treatment for every disease, but making sure the treatments we have already developed are being used in every possible way. I speak with Dr. David Fajgenbaum (Fay-gen-baum), a Professor of Translational Medicine and Human Genetics at the University of Pennsylvania School of Medicine, and President of Every Cure.…

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Alcohol-Associated Hepatitis Treatment on the Horizon!!! Dr. Jim Brown, CEO of DURECT 14:52

3M ago14:52

14:52

Dr. Jim Brown from DURECT talks about their clinical trials for Alcohol-Associated Hepatitis, a condition for which there is no approved treatment.Moira Gunn

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Building Technology and Solving Problems!!! Dave Pacitti, President & Head of the Americas, Siemens Healthineers 20:30

3M ago20:30

20:30

When is a medical technology company more than a medical technology company? We’ll hear all about it when I speak with Dave Pacitti, the President and Head of the Americas at Siemens Healthineers. They’re out to solve problems bigger than the products they are known for.Moira Gunn

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XPrize Foundation and $101 Million!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent 11:14

3M ago11:14

11:14

Tech Nation Health Chief Correspondent Dr. Daniel Kraft talks about the newest XPrize worth an unprecedented $101 Million.Moira Gunn

1
Wound Healing 2.0!!! Dr. Nik Sopko, Chief Scientific Officer at PolarityTE 15:19

4M ago15:19

15:19

Dr. Nik Sopko, the Chief Scientific Officer of PolarityTE talks about their design for wound healing. Their first treatment candidate is diabetic foot ulcers.Moira Gunn

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Harnessing Natural Killer Cells!!! Dr. Eric Vivier, SVP & CSO of Innate Pharma 20:25

4M ago20:25

20:25

Dr. Eric Vivier from Innate Pharma in Marseilles tells us about the next wave of immunotherapy treatments – harnessing Natural Killer cells.Moira Gunn

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Can Every Medicine Be a Pill??? Dr. Ray Stevens, CEO of ShouTi Pharma 24:24

4M ago24:24

24:24

Dr. Ray Stevens, CEO of ShouTi Pharma, talks about their approach in turning IV drugs into pills. Current projects include Diabetes and obesity, and two Pulmonary and Cardiovascular disorders. And these are just their first candidates …Moira Gunn

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Gut-Brain Connections to Autism, Parkinson's, and More!!! Dr. Stewart Campbell, CEO Axial Therapeutics 25:38

4M ago25:38

25:38

Dr. Stewart Campbell, CEO of Axial Therapeutics, about their groundbreaking work in Autism–related irritability in teenagers, in Parkinson’s, and in complementing the latest cancer treatments.Moira Gunn

1
Ancient Viruses in our DNA??? Dr. Neil Shubin, Professor & Author University of Chicago 28:55

4M ago28:55

28:55

On this week’s BioTech Nation University of Chicago professor Dr. Neil Shubin talks about his book “Some Assembly required … Decoding Four Billion Years of Life, from Ancient Fossils to DNA.” Ancient viruses in our DNA? And what about “jumping genes”?Moira Gunn

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Treating Diseases with Brain Implants??? Nicolas Vachicouras, CEO & Co-Founder Neurosoft Bioelectronics 15:44

5M ago15:44

15:44

This week we visit the brain, and look at what a flexible brain implant might do – from sensing how your brain is working to actual treatment. Nicolas Vachicouras from Neurosoft Bioelectronics in Geneva, Switzerland talks about the target for their first treatment: severe tinnitus.Moira Gunn

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The Next Ozempic or Wegovy... But Without the Injection??? Dr. Steffen-Sebastian Bolz, CSO, Aphaia (ah-phi-ah) Pharma 24:36

5M ago24:36

24:36

What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.Moira Gunn

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Who Could Forget About Dolly The Sheep??? Sir Ian Wilmut, Director, Scottish Centre for Regenerative Medicine 29:51

5M ago29:51

29:51

We honor Sir Ian Wilmut, the Scottish embryologist who gained worldwide renown as the leader of the scientific research group that cloned the equally famous Dolly. With his recent passing, we air our 2007 BioTech Nation interview, when David Ewing Duncan and I spoke with Dr. Wilmut on the 10th anniversary of Dolly’s birth.…

1
Everybody Has a Thyroid... What Could Go Wrong??? Dr. Mark Sumeray, CMO of Amolyt Pharma 28:19

5M ago28:19

28:19

Dr. Mark Sumeray from Amolyt Pharma talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.Moira Gunn

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It’s All About Cancer, and Covid??? Dr. Andrew Allen, President, CEO, & Co-Founder Gritstone Bio 43:28

6M ago43:28

43:28

This week on BioTech Nation, Andrew Allen, President, CEO and Co-Founder of Gritstone Bio – a full spectrum look at how cancer starts and cancer treatments have developed … and what next-generation treatment means today with Gritstone’s work in colorectal cancer. And wait for it … the next generation of Covid vaccines.…

1
Is Medical School Curriculum Outdated??? Dr. Daniel Kraft, Tech Nation Health Chief Correspondent 11:43

6M ago11:43

11:43

Tech Nation Health Chief Correspondent Dr. Daniel Kraft talks about how Medical Schools decide what to teach. You might be surprised that it’s based on the Flexner Report … written in … 1910. Is it time for a do-over? And what might that be?Moira Gunn

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Your Digital Twin May Already Exist!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent 6:50

6M ago6:50

6:50

Tech Nation Health Chief Correspondent Dr. Daniel Kraft talks about your Digital Twin … your Digital Twin … yes, you have one.Moira Gunn

1
A New Approach To Treating Diabetes... Dr. Anthony Japour, President & CEO, iTolerance 12:40

6M ago12:40

12:40

Dr. Anthony Japour, President and CEO from iTolerance in Miami, Florida tells us about implanting insulin-producing cells in your pancreas – it’s been tried before, but they have a new approach which just might work.Moira Gunn

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What's New in Digital Health!!! Dr. Daniel Kraft, Tech Nation Health Chief Correspondent 11:17

7M ago11:17

11:17

Tech Nation Health Chief Correspondent Dr. Daniel Kraft tells us about the explosion of digital health.Moira Gunn

1
Google's First Radio Interview Ever!!! Larry Page & Sergey Brin, Co-Founders, Google 28:15

7M ago28:15

28:15

It’s the 25th anniversary of the founding of Google … and 23 years ago, Google founders - Larry Page and Sergey Brin – came to the Tech Nation studios to do their very first radio interview. There’s lots to learn there, including they believed what humans demanded of search, and why they did what they did.…

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Old Dog, New Tricks ??? ... Dr. Robert Ladner, CEO & Founder, CV6 Therapeutics 21:11

7M ago21:11

21:11

Dr. Robert Ladner, the Founder of CV6 Therapeutics in Belfast, Northern Ireland, tells us about their work to make a cornerstone cancer chemotherapy, even more effective. First trials are in colorectal and gastrointestinal cancers...Moira Gunn

1
Can Good Viruses Kill Deadly Infections??? Tom Ireland, Science Journalist & Author 28:57

7M ago28:57

28:57

Science journalist Tom Ireland tells us about a burgeoning field of science, which is changing the fight to successfully treat antibiotic infections. His book is “The Good Virus: The Amazing Story and Forgotten Promise of the Phage”.Moira Gunn

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Osteoarthritis... Mostly in the Knee, But Pick a Joint!!! Dr. Diem Nguyen, CEO of Xalud Therapeutics 18:39

7M ago18:39

18:39

Osteoarthritis – mostly in the knee, but pick a joint. Dr. Diem (Zem) Nguyen (N’Win) is the CEO of Xalud (Za-lood) Therapeutics. We’ll talk about their work to reduce the inflammation that drives pain. It’s now in human clinical trials.Moira Gunn

1
Why Do AI One Way, When You Can Do it 25??? Dr. Ben Thomas and Dermot Tierney, CEO & CCO, Amply Discovery 21:49

8M ago21:49

21:49

Why use one AI approach when you can use 25? CEO Dr. Ben Thomas and Chief Commercial Officer Dermot Tierney from Amply Discovery talks about how their novel approach to AI in drug discovery.Moira Gunn

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Acute Cannabis Intoxication... Is There An Antidote??? Dr. Ken Cundy, CSO at Anebulo Pharmaceuticals 18:53

8M ago18:53

18:53

Modern cannabis products, with higher potency than those from the past, can lead to acute cannabis intoxication. Anebulo Pharmaceuticals, led by Chief Scientific Officer Dr. Ken Cundy, is working on an antidote that counteracts the negative effects of THC overdose, potentially benefiting both adults and children.…

1
Did That Change To My Prescription Work??? -- Dr. Kal Patel, CEO, BrightInsight 35:13

8M ago35:13

35:13

Continuous monitoring ... when we want it, when we don’t, should we share it? Or not. Or perhaps just part of it. Dr. Kal Patel, the Co-Founder and CEO of BrightInsight talks about this brave new frontier.Moira Gunn

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Gliobastoma + New View on Clinical Trials... Dr. Fahar Merchant, President & CEO Medicenna Therapeutics 22:38

8M ago22:38

22:38

Glioblastoma is the most aggressive form of brain cancer, and progress in treating Glioblastoma has been elusive. Now, Toronto-based Medicenna has completed a successful Phase 2 with its innovative drug, and is now deep into planning the Phase 3 Trial. Also of interest, the FDA agreed to an unprecedented approach in Phase 2, which not only yields b…

1
Innovation in Head & Neck Cancers!!! Dr. Mark Newman, CSO, GeoVax 14:40

9M ago14:40

14:40

In this week's BioTech Nation, we discuss Geovax, a company working on a novel approach to treat head and neck cancers, which are often difficult to treat after standard options have been exhausted. Geovax is developing A2 component therapy, using an enzyme delivered directly to the tumor by a needle injection, followed by an infusion of an inactiv…

1
We Still Can't Ignore Long Covid... Dr. Jeffrey Cleland, CEO Ashvattha Therapeutics 9:54

9M ago9:54

9:54

In this week's episode of Biotech Nation, Dr. Jeffrey Cleland, the President and CEO of Ashvattha Therapeutics, discusses their drug development efforts to address long COVID. They discuss the definition of long COVID by the World Health Organization, the prevalence of the condition, and the chronic inflammation that occurs in the body, including t…

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Can The Time Needed for CAR-T be shortened? EXUMA Says Yes!!! Dr. Gregory Frost, CEO, EXUMA Biotech 10:21

9M ago10:21

10:21

In this week's episode of Biotech Nation, Dr. Greg Frost, CEO of Exuma Biotech, discusses their innovative approaches to cancer treatment. They are working on a method to shorten the time and eliminate hospital stays for CAR-T therapy, while also developing a new technology called G-car that combines T cells and NK cells to create a more gentle and…

1
Temporal Lobe Epilepsy - TLE - Will Cell Therapy Work??? Dr. Cory Nicholas, CEO, Neurona Therapeutics 24:21

9M ago24:21

24:21

A new cell therapy, just entering human clinical trials. It focuses on a particular type of Epilepsy - Temporal Lobe Epilepsy. I speak with Dr. Cory Nicholas, the Co-Founder and CEO of Neurona Therapeutics, about their idea, what they’ve done, and how they plan to approach testing this unprecedented treatment.…

1
New Hope For Glaucoma... Dr. Chris Nave, Managing Director of Brandon Capital and Chair of PolyActiva 9:12

10M ago9:12

9:12

Join us as Dr. Chris Nave, the managing director of Brandon Capital and Chair of PolyActiva, reveals groundbreaking advancements in eye treatments on this week's episode of Biotech Nation! Discover how their innovative technology is revolutionizing the way we deliver drugs to the eye, offering extended therapy periods and eliminating the need for f…

1
The Beauty Contest... Winner Goes to Phase I - Dr. Richard Austin, Founder & CEO Reglagene 16:36

10M ago16:36

16:36

Join Dr. Richard Austin, Founder and CEO of Reglagene, as he reveals the intense process of selecting the most promising drug candidate for treating brain cancer. Delve into the intriguing world of the "Bake Off" or "beauty contest" where molecules compete to be the breakthrough therapy in human clinical trials. Discover the challenges of penetrati…

1
Sticky Proteins??? Alzheimer's, Parkinson's, and ALS...Dr. Maria Maccecchini, President & CEO, Annovis Bio 19:20

10M ago19:20

19:20

This week we explore the commonalities among neurodegenerative disorders such as Alzheimer's, Parkinson's, and ALS. Dr. Maria Macccecchini, Founder and CEO of Annovis Bio, discusses the role of sticky proteins in these diseases and how her company is developing a drug to prevent the aggregation of these proteins. The episode also touches on their o…

1
When Your Distant Cousins ID You For Murder… Ed Humes, Author of "The Forever Witness" 49:33

10M ago49:33

49:33

Moira speaks with Pulitzer Prize-winning author, Ed Humes. His latest is “The Forever Witness … How DNA and Genealogy Solved a Cold Case Double Murder.” We get an object lesson in the Three Ages of DNA, and while it reads like a fast-paced Cold Case on steroids – it provides details no fiction writer would dare to make up, like the unexpected invol…

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Are Fibroblasts All Over My Body??? Dr. Hamid Khoja, CSO at FibroBiologics 25:13

11M ago25:13

25:13

Dr. Hamid Khoja, Chief Scientific Officer of Fibro Biologics, discusses the potential of fibroblasts in regenerative medicine, highlighting their abundance and diverse functions in the body. He shares insights from their ongoing human clinical trials, including the use of fibroblasts for treating degenerative disc disease and multiple sclerosis. Dr…

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Engineering Viruses to Treat Solid Tumors... Dr. Paul Peter Tak, CEO of Candel Therapeutics 22:24

11M ago22:24

22:24

Dr. Paul Peter Tack, CEO of Candel Therapeutics, unveils their groundbreaking approach to cancer treatments using engineered viruses. Discover how these viruses are harnessed to target solid tumors, deliver therapeutic genes, and activate the patient's immune system for a powerful anti-cancer response.…

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AI Three Different Ways to a New Drug??? Dr. Francois Vigneault, Co-Founder & CEO Shape Therapeutics 27:35

11M ago27:35

27:35

Discover the limitless potential of mRNA engineering as Dr. Francois Vigneault, Co-Founder and CEO of Shape Therapeutics, discusses their groundbreaking work in using mRNA to address genetic mutations in diseases like Parkinson's and Alzheimer's, offering hope for effective treatments and prevention strategies. Join us as we delve into the world of…

1
Fighting the Most Advanced Prostate Cancer... Dr. Philip Kantoff, CEO Convergent Therapeutics 10:29

11M ago10:29

10:29

200,000 men at diagnosed each year with Prostate cancer … beginning a journey of many successive treatments. Still, 35,000 men die as a result of prostate cancer. Convergent Therapeutics is focusing on the most advanced, intractable cases of prostate cancer. We speak with, Dr. Philip Kantoff is its Co-Founder, Chief Medical Officer and CEO.…

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A Different Approach, A New Cancer Drug... Dr. Paul Lammers, CEO Triumvira Immunologics 13:31

11M ago13:31

13:31

Cancer treatments which work with the immune system are making great strides, with Keytruda from Merck being perhaps the best known. Still there is much work to be done – both in developing unprecedented new treatments, as well as treatments which might combine with our existing treatments to make them even more effective. Triumvera (try-um-VEERA) …

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